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- Eyesight to the Blind
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- Eyesight to the Blind: The Promise of Retinal Prosthetics
Various modifications have allowed improved edge-detection and image enhancement, which took place during early studies on shape and object recognition. However, the potential additional benefit is still uncertain. The makers of Argus II have alluded to a next-generation device with electrodes, with the possibility of the addition of peripheral electrodes. Although more progress is needed, the ability to offer functional vision in those who otherwise would have had none is a remarkable feat in itself.
The Argus II retinal prosthesis is the end result of years of hard work on the part of innumerable investigators who contributed their time, ideas and efforts. Further, were it not for the altruism of dozens of volunteers during the trials of both the Argus I and Argus II, this work would not have been possible. Luminaries in Artificial Vision While significant progress in treating degenerative outer retinal disease has been made in the past several decades, the scientific exploration that ultimately led us to the present day began as early as the mid 18th century.
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French physician Charles LeRoy created the sensation of light in the blind by passing electrical currents around the head in In the s, Button and Puttnam implanted four occipital lobe electrodes with percutaneous connections in three blind patients. Twenty-five years of focused work on the epiretinal implant around the globe has led us to the Argus II.
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Humayun, comprised the three-person team that launched the research that eventually led to the Argus implant. In , Dr. While at Wilmer, the intraocular retinal prosthesis laboratory obtained three important new collaborators: Gislin Dagnelie, PhD, for his knowledge of psychophysics and simulation studies, MD-PhD student Robert Greenberg and postdoctoral researcher James Weiland, PhD, from the University of Michigan for his expertise in electrode materials and neural stimulation.
Factors affecting perceptual thresholds in epiretinal prostheses. Invest Ophthalmol Vis Sci. Predicting visual sensitivity in retinal prosthesis patients. Perceptual thresholds and electrode impedance in three retinal prosthesis subjects.
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Visual performance using a retinal prosthesis in three subjects with retinitis pigmentosa. Am J Ophthalmol. Accessed 20 Jan Second Sight Medical Products. Available at www. Accessed January 20, Preservation of the inner retina in retinitis pigmentosa.
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A morphometric analysis. Arch Ophthalmol. Morphometric analysis of the macula in eyes with geographic atrophy due to age-related macular degeneration. Morphometric analysis of the macula in eyes with disciform age-related macular degeneration. Five-year safety and performance results from the Argus II retinal prosthesis system clinical trial. Long-term results from an epiretinal prosthesis to restore sight to the blind. The Argus II retinal prosthesis: month outcomes from a single-study center. The use of Argus II retinal prosthesis by blind subjects to achieve localisation and pre- hension of objects in 3-dimensional space.
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Graefes Arch Clin Exp Ophthalmol. The Argus II retinal prosthesis system: an overview. Petrs-Silva H, Linden R. Advances in gene therapy technologies to treat retinitis pigmentosa.
Clin Ophthalmol. Retinal repair with induced pluripotent stem cells. Transl Res. Subretinal visual implant alpha IMS - Clinical trial interim report. Vision Res. First-in-human trial of a novel suprachoroidal retinal prosthesis. PLoS One. The functional performance of the Argus II retinal prosthesis. Expert Rev Med Dev. LeRoy C. Button J, Puttnam T. Visual responses to cortical stimulation in the blind.
J Iowa Med Soc. The sensations produced by electrical stimulation of the visual cortex. J Physiol Lond. A model for intracortical visual prosthesis research. Artf Org. Invest Ophthalmol Visual Sci. Your email address will not be published. Save my name, email, and website in this browser for the next time I comment.
Eyesight to the Blind: The Promise of Retinal Prosthetics
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